It's easy to save anywhere in the game. Just open the console (the ~ or TILDE key) and type \save_game. If you can bind the command to an unused key, you will be able to quicksave any time with a press of the button. You may otherwise just type in the command normally each time you want to save.

Submitted by Lawrence Cade

Just add -DEVMODE to the end of the executable command line if the save command is not working.

Submitted by Chris Cheng