• The first Plasmid, and the first weapon you find are the best in the game.
  • Zap em and whack em, that's all you need to know.
  • Research everything, it's well worth it. The Houdini Splicers are well worth your time since you'll get the most useful Tonic in the game.
  • Get over being scared, the enemies aren't that bad.
  • Explore every room in every area and you'll get more out of the game.